Hayes KC, Carey RE, Schmidt SY (May 1975). "Retinal degeneration associated with taurine deficiency in the cat". Science. 188 (4191): 949–951. Bibcode: 1975Sci...188..949H. doi: 10.1126/science.1138364. PMID 1138364. Prof. John Chiang, an expert in bile acid metabolism, stated that “bile acids maintain liver metabolic homeostasis and have anti-inflammatory properties.” Volatiles/ gases (e.g., chloral hydrate, chloroform, desflurane, diethyl ether (ether), enflurane, halothane, isoflurane, methoxyflurane, sevoflurane, toluene, trichloroethane (methyl chloroform), trichloroethylene)

A study published in the Journal of Neurogastroenterology and Motility suggests that bile salts can be a useful therapeutic tool in managing constipation. The human body naturally produces digestive enzymes to break down food molecules into smaller, easily digestible substances. Many people's bodies generate all the enzymes needed for digestion. However, if you have an enzyme deficiency, you may have trouble breaking down certain foods and experience uncomfortable symptoms like bloating, gas, and diarrhea. A common example is lactose intolerance, which is when the body doesn’t make enough of the enzyme lactase, needed to digest lactose (milk sugar).While ox bile is generally well tolerated, it can cause abdominal pain, diarrhea, headaches, and immune reactions in some individuals. These side effects typically disappear once you stop taking ox bile supplements. While bile salts are generally well-tolerated, taking ox bile supplements could make these three health conditions worse: We have been using Horbäach's Ox Bile Supplement for a few weeks now and have noticed a significant improvement in our digestion. The capsules are easy to swallow and the recommended dosage of 1,000 mg per serving is just right. We appreciate that the supplement is naturally free of gluten, wheat, yeast, milk, lactose, soy, artificial color & flavor, and non-GMO. Most of these side effects are typically mild and will disappear once you stop taking bile salts. However, if you experience severe or persistent symptoms, it’s important to consult with a healthcare professional. Inflammation in the smallest ducts spreads and eventually damages other cells in the liver. As the cells die, they're replaced by scar tissue (fibrosis) that can lead to cirrhosis. Cirrhosis is scarring of liver tissue that makes it difficult for your liver to work properly. Risk factors

Taurine is also produced by the transsulfuration pathway, which converts homocysteine into cystathionine. The cystathionine is then converted to hypotaurine by the sequential action of three enzymes: cystathionine gamma-lyase, cysteine dioxygenase, and cysteine sulfinic acid decarboxylase. Hypotaurine is then oxidized to taurine as described above. [16]We have personally used the LionHeart Supplements Ox Bile Supplement and have noticed significant improvements in our digestion and overall gut health. The purified ox bile salts help to break down fats and improve nutrient absorption, while also providing relief from gas and bloating. Moreover, Thorne is a trusted brand in the supplement industry, with collaboration with Mayo Clinic on wellness research and content. The supplement is also free from common allergens such as soy, dairy, and gluten, making it suitable for most people. Fatty deposits (xanthomas) on the skin around the eyes, eyelids or in the creases of the palms, soles, elbows or knees

Taurine is named after Latin taurus ( cognate to Ancient Greek ταῦρος, taûros) meaning bull or ox, as it was first isolated from ox bile in 1827 by German scientists Friedrich Tiedemann and Leopold Gmelin. [2] It was discovered in human bile in 1846 by Edmund Ronalds. [3] Functional dyspepsia is a condition where you have indigestion without a clear cause. While there is no enzyme deficiency with this condition, a small amount of research has shown the benefit of taking lipase before fat-rich meals. Bile salts are a component of bile, while ox bile is a whole extract of bile from oxen. Bile salts are often used in combination with ox bile in supplements to aid in digestion. What are the potential side effects of taking an ox bile supplement? Achufusi TGO, Sharma A, Zamora EA, Manocha D. Small intestinal bacterial overgrowth: Comprehensive review of diagnosis, prevention, and treatment methods. Cureus. 2020;12(6):e8860. doi:10.7759/cureus.8860Weak bones (osteoporosis). People with primary biliary cholangitis have an increased risk of weak, brittle bones that may break more easily. Taking ox bile supplements is generally considered safe, but some people may experience side effects. Marvel CS, Bailey CF, Cortese F (1938). "Taurine". Organic Syntheses. 18: 77. doi: 10.15227/orgsyn.018.0077.

Taurine And Its Importance In Cat Foods". Iams Cat Nutrition Library. 2004. Archived from the original on 2006-10-19 . Retrieved 2006-08-22.

I typically recommend taking bile salts before or after a meal to speed up digestion and support digestive health,” says Dr. Berg. “However, eating stimulates stomach acid, which can lower the effectiveness of bile salts, and some people benefit from taking ox bile on an empty stomach.” Gall Plus provides a unique blend of ingredients which may help to support the health of the pancreas, liver and gallbladder and assist in the emulsification and absorption of dietary fats. In your body, the liver is responsible for the production of bile which is then transported to the gallbladder where it is stored. When you consume dietary fats, bile is released from the gallbladder (ideally) and the pancreas produces specific enzymes to help break down fat molecules into even smaller molecules so they can be utilised by the body.